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Gene/Clone	Species	Stage	Anatomy Item	Experimenter
spry2	xenopus		pre-chordal neural plate [+] anterior neural fold,optic field,pre-chordal neural plate border,anterior neural tube,choroid fissure,eye,eye primordium,forebrain,iris,midbrain,optic nerve,optic stalk,optic tectum,optic vesicle,ventral septum,diencephalon,dorsal telencephalon,posterior commissure,anterior commissure,ventral pallidum,nucleus of the diagonal band,bipolar neuron,optic stalk,mesencephalic artery,anterior amygdala,optic chiasm,posteroventral tegmental nucleus,retinal stem cell,pallidum,anteroventral tegmental nucleus,peripheral retina,caudal tuberal region,anterior thalamic nucleus,olfactory bulb,cornea,ventral pallium,pupil,granule cell,thalamus,choroid,dorsal tegmentum,sclera,horizontal cell,ventral hypothalamic nucleus,mitral cell,retinal inner plexiform layer,optic fiber layer,suprachiasmatic nucleus,ciliary marginal zone,central retina,medial ganglionic eminence,retinal stem cell region,lateral septum,lateral amygdala,lens transitional zone,mesencephalic vein,preoptic area,pigment layer,dorsal pallium,inner limiting membrane,retinal outer nuclear layer,hypothalamus,choroid fissure,retinal ganglion cell,midbrain tegmentum,magnocellular preoptic nucleus,subcommissural organ,retinal pigmented epithelium,ventromedial thalamic nucleus,retromammillary area,nucleus accumbens,pineal gland,prethalamus,accessory olfactory bulb,pallium,external plexiform layer of the olfactory bulb,retinal inner nuclear layer,optic tract,eminentia thalami,anterior entopeduncular region,posterior tectum,conjunctiva,rostral tuberal region,prethalamus basal plate,habenula,amacrine cell,telencephalon septum,infundibulum,outer segment cilium,granule cell layer of the olfactory bulb,neurohypophysis,eye photoreceptor cell,optic tectum,adenohypophysis,retinal layer,ventricular layer of the optic tectum,glial endfoot,radial glial cell,laterodorsal tegmental nucleus,lateral forebrain bundle,medial pallium,dorsal habenular nucleus,ventral habenular nucleus,retinal ganglion cell layer,retinal neural layer,melanotrope,pars intermedia,retinal progenitor cell region,anterodorsal tegmental nucleus,prosomere,lens fiber cell mass,supraoptoparaventricular region,torus semicircularis,cell body layer of the optic tectum,oculomotor motornucleus,ciliary body,iris,telencephalon,striatum,lateral pallium,pretectum,optic nerve,subthalamic nucleus,retina,lateral hypothalamic nucleus,dorsal pallidum,ventrolateral thalamic nucleus,central nucleus of the thalamus,bed nucleus of the stria terminalis,dorsal septum,pars nervosa,tuberal region,anterior entopeduncular nucleus,zona limitans intrathalamica,lens epithelium,pars distalis,medial septum,mammilary region,third ventricle,medial amygdala,prosomere 4,central amygdala,retinal outer plexiform layer,subpallium,posterodorsal tegmental nucleus,trochlear motornucleus,neuropil of the optic tectum,mitral cell layer of the olfactory bulb,anterior hypothalamus,hypophysis,basal forebrain,lens placode,dorsal thalamus,Mueller cell,ventral tegmentum,globe,prosomere 6,optic disc,lateral ganglionic eminence,prosomere 5,retinal progenitor cell,lens,amygdala,outer segment disk,posterior hypothalamus,outer limiting membrane,lower eyelid,glomerular layer of the olfactory bulb,photoreceptor layer,anterior tectum,basal ganglion

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Expression summary for spry2

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Experiment	Species	Images	Stages	Anatomy	Assay
FGF signal interpretation is directed by Sprouty and Spred proteins during mesoderm formation. Paper	laevis	1 image	tailbud stage	forebrain	in situ hybridization
Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo. Paper	tropicalis	1 image	NF stage 28	forebrain	in situ hybridization
Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo. Paper	tropicalis	1 image	NF stage 28	forebrain	in situ hybridization
Retinoic acid is a key regulatory switch determining the difference between lung and thyroid fates in Xenopus laevis. Paper	laevis	1 image	NF stage 37 and 38	lens, midbrain, pineal gland	in situ hybridization
Fgf is required to regulate anterior-posterior patterning in the Xenopus lateral plate mesoderm. Paper	laevis	1 image	NF stage 32	forebrain	in situ hybridization
Wang JH et al. (2011) Assay Xenbase Image	laevis	1 image	NF stage 29 and 30	forebrain, lens placode, midbrain	in situ hybridization
Chen JA et al. (2005) Assay Paper	tropicalis	1 image	NF stage 17 to NF stage 29 and 30	forebrain, pre-chordal neural plate	in situ hybridization
Patient Lab	laevis	2 images	NF stage 29 and 30	eye, forebrain	in situ hybridization
Prolonged FGF signaling is necessary for lung and liver induction in Xenopus. Paper	laevis	1 image	NF stage 35 and 36	eye, forebrain	in situ hybridization
Henry Lab Assay Henry Lab	laevis	1 image	NF stage 21 to NF stage 35 and 36	lens	in situ hybridization
Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway. Paper	laevis	1 image	NF stage 18	optic field	in situ hybridization
Cornea-lens transdifferentiation library Unigene laevis cDNA library	laevis		NF stage 50 to NF stage 52	cornea	cDNA Library

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