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GEO Series: GSE48663

Title: In vivo T-box Transcription Factor Profiling Reveals Joint Regulation of Embryonic Neuro-mesodermal Bipotency

Summary

Brachyury (Xbra/Xbra3) knock-down embryos of the frog Xenopus tropicalis were profiled to quantify neuro-mesodermal cell fate switches at a transcriptional level.


Contributors: George Gentsch, George Gentsch, James Smith

Experiment Type: Transcriptional profiling of Xbra/Xbra3 double morphants at early tadpole stage (RNA-Seq) in biological triplicates.

Experiment Reagents: hbg1 cMO1, tbxt MO2, tbxt MO3,

Article: Xenbase, PubMed

Source: NCBI GEO, Xenbase FTP

Samples:
Sample View GSMs Assay Type
WE + hbg1 MO - NF32 GSM1183059  GSM1183060  GSM1183061  RNA-Seq
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection hbg1 cMO1 hbg1 NF stage 1 zygote
Conditions:
Tissue Assay Stages ChIP Antibody
embryo NF stage 32  
   WE + t2 MO + t MO - NF32 DEG GSM1183056  GSM1183057  GSM1183058  RNA-Seq
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection tbxt MO2 tbxt NF stage 1 zygote
morpholino injection tbxt.2 MO3 tbxt.2 NF stage 1 zygote
morpholino injection tbxt.2 MO4 tbxt.2 NF stage 1 zygote
morpholino injection tbxt MO3 tbxt NF stage 1 zygote
Conditions:
Tissue Assay Stages ChIP Antibody
embryo NF stage 32  
WE - NF20 GSM1183062  RNA-Seq
Background: Xtr.Outbred
Conditions:
Tissue Assay Stages ChIP Antibody
embryo NF stage 20  
Select All DEG      Select All 
Xtr   
Xla 

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