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GEO Series: GSE48663

Title: In vivo T-box Transcription Factor Profiling Reveals Joint Regulation of Embryonic Neuro-mesodermal Bipotency

Summary

Brachyury (Xbra/Xbra3) knock-down embryos of the frog Xenopus tropicalis were profiled to quantify neuro-mesodermal cell fate switches at a transcriptional level.


Contributors: George Gentsch, George Gentsch, James Smith

Experiment Type: Transcriptional profiling of Xbra/Xbra3 double morphants at early tadpole stage (RNA-Seq) in biological triplicates.

Experiment Reagents: hbg1 cMO1, tbxt MO2, tbxt MO3,

Article: Xenbase, PubMed

Source: NCBI GEO, Xenbase FTP

Samples:
Sample View GSMs Assay Type
WE + hbg1 MO - NF32 GSM1183059  GSM1183060  GSM1183061  RNA-Seq
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection hbg1 cMO1 hbg1 NF1 zygote
Conditions:
Tissue Assay Stages ChIP Antibody
embryo NF32  
   WE + t2 MO + t MO - NF32 DEG GSM1183056  GSM1183057  GSM1183058  RNA-Seq
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection tbxt MO2 tbxt NF1 zygote
morpholino injection tbxt.2 MO3 tbxt.2 NF1 zygote
morpholino injection tbxt.2 MO4 tbxt.2 NF1 zygote
morpholino injection tbxt MO3 tbxt NF1 zygote
Conditions:
Tissue Assay Stages ChIP Antibody
embryo NF32  
WE - NF20 GSM1183062  RNA-Seq
Background: Xtr.Outbred
Conditions:
Tissue Assay Stages ChIP Antibody
embryo NF20  
Select All 
Xtr   
Xla 

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