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brevican: member of the aggrecan/versican family. Expression first observed in the notochord of neurula stage embryos. In addition to this, in tailbuds, Xbcan was also found to be expressed within the fifth and sixth rhombomere of the hindbrain. In tadpole stage embryos, expression was furthermore observed in periventricular regions of the developing brain and the rostral part of the spinal cord.

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Stage 17. Expression is restricted to the developing notochord (n) Cleared late neurula stage (NF 25) embryo: beside the notochord, Xbcan transcription takes place in a stripe-like pattern in the fifth and sixth rhombomeres (marked by an arrow head) stage 30-31  
     
  Tadpole stage embryo (NF 40): Xbcan expression is detectable in various brain regions other than the hindbrain.    
       
       
       
       
       
       
Cloned by: Original description:
Sander et al. in Günter Lepperdinger's laboratory Sander V, Mullegger J, Lepperdinger G. Xenopus brevican is expressed in the notochord and the brain during early embryogenesis. Mech Dev. 2001 Apr;102(1-2):251-3.
Images submitted by: Sequence
Assembled from Mechanisms of Development vol 102, ©Elsevier, 2001
Probe available from: Other papers by:
Günter Lepperdinger Sander | Lepperdinger
In situ probe details: cDNA in pBluescript (derived from ZapII lambda clone) Other papers on:
plasmid name: antisense RE cut: antisense transcription: Xenopus brevican
mRNA generation
plasmid name: sense RE cut: sense transcription:

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