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sonic hedgehog, shh: axial mesoderm, notochord, floor plate
Click on images to view enlargements (6K to 7K, < 2 seconds).
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| early gastrula, vegetal view | mid-gastrula, vegetal view | Sagital section of stage 12.5 gastrula. cm= chordal mesoderm yp= yolk plug |
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| D. | E. | F. |
| stage 13 neurula, lateral view. transcripts in neural plate and notochord |
stage 28,
lateral view. arrow indicates prospective thyroid, r=Rathke's pouch, n
= notochord, fp = floor plate, br = brain (ventral only), i = infundibulum. |
stage 30 shh is progressively activated from anterior to posterior in the visceral arches |
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| stage 32 |
| Cloned by: | Original description: | ||
| Ekker SC, McGrew LL, Lai CJ, Lee JJ, von Kessler DP, Moon RT, Beachy PA. Distinct expression and shared activities of members of the hedgehog gene family of Xenopus laevis. Development. 1995 Aug;121(8):2337-47. | |||
| Images submitted by: | Sequence | ||
| Andres Carrasco | |||
| Probe available from: | Other papers by: | ||
| Andres Carrasco | Carrasco / Ekker / Beachy | ||
| In situ probe details: | Other papers on: | ||
| plasmid name: | antisense RE cut: | antisense transcription: | Xenopus shh |
| mRNA generation | |||
| plasmid name: | sense RE cut: | sense transcription: | |
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