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Many embryonic species are initially transcriptionally quiescent after fertilization. In this issue of Developmental Cell, Blythe et al. reveal that beta-catenin acts very early in Xenopus development to specifically modify the chromatin of organizer genes, poising them for rapid activation when transcription begins.
Belenkaya,
pygopus Encodes a nuclear protein essential for wingless/Wnt signaling.
2002, Pubmed,
Xenbase
Belenkaya,
pygopus Encodes a nuclear protein essential for wingless/Wnt signaling.
2002,
Pubmed
,
Xenbase
Blythe,
beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2.
2010,
Pubmed
,
Xenbase
De Robertis,
Spemann's organizer and the self-regulation of embryonic fields.
2009,
Pubmed
,
Xenbase
Kennedy,
A co-dependent requirement of xBcl9 and Pygopus for embryonic body axis development in Xenopus.
2010,
Pubmed
,
Xenbase
Larabell,
Establishment of the dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in beta-catenin that are modulated by the Wnt signaling pathway.
1997,
Pubmed
,
Xenbase
Mosimann,
Beta-catenin hits chromatin: regulation of Wnt target gene activation.
2009,
Pubmed
Weaver,
Move it or lose it: axis specification in Xenopus.
2004,
Pubmed
,
Xenbase
Yang,
Beta-catenin/Tcf-regulated transcription prior to the midblastula transition.
2002,
Pubmed
,
Xenbase
