Regulation of the meiotic cell cycle in oocytes.
The mitotic and meiotic cell cycle share many regulators, but there are also important differences between the two processes. The meiotic maturation of Xenopus oocytes has proved useful for understanding the regulation of Cdc2-cyclin-B, a key activator of G2/M progression. New insights have been made recently into the signalling mechanisms that induce G2-arrested oocytes to resume and complete the meiotic cell cycle.
PubMed ID: 11063930
Article link: Curr Opin Cell Biol.
Genes referenced: cdk1 pold1