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Mech Dev June 1, 2000; 94 (1-2): 189-93.

XSIP1, a Xenopus zinc finger/homeodomain encoding gene highly expressed during early neural development.

van Grunsven LA , Papin C , Avalosse B , Opdecamp K , Huylebroeck D , Smith JC , Bellefroid EJ .

We have isolated a Xenopus homologue of the zinc finger/homeodomain-containing transcriptional repressor Smad-interacting protein-1 (SIP1) from mouse. XSIP1 is activated at the early gastrula stage and transcription occurs throughout embryogenesis. At the beginning of gastrulation, XSIP1 is strongly expressed in prospective neurectoderm. At the neurula stage, XSIP1 is highly expressed within the neural plate but weakly in the dorsal midline. At later stages of development transcripts are detected primarily within the neural tube and neural crest. In the adult, XSIP1 expression is detected at variable levels in several organs.

PubMed ID: 10842070
Article link: Mech Dev

Species referenced: Xenopus laevis
Genes referenced: mcf2 odc1 zeb2 znf469

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