Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-12234
Curr Opin Genet Dev 1999 Oct 01;95:559-65. doi: 10.1016/s0959-437x(99)00011-8.
Show Gene links Show Anatomy links

Notch around the clock.

Pourquié O .


???displayArticle.abstract???
The establishment of a segmental pattern within the vertebrate body plan is achieved during embryogenesis by the somitogenesis process. Two molecular systems have been implicated in this phenomenon: a molecular clock linked to vertebrate segmentation and the Notch signalling pathway. Rhythmic expression of the Lunatic Fringe gene in the presomitic mesoderm has now provided a link between these two systems.

???displayArticle.pubmedLink??? 10508694
???displayArticle.link??? Curr Opin Genet Dev


Species referenced: Xenopus
Genes referenced: clock notch1