He Ml , Wen L , Campbell CE , Wu JY , Rao Y .

DK48796 NIDDK NIH HHS , R01 CA114197-01A2 NCI NIH HHS , R01 EY014576-03 NEI NIH HHS , R01 GM070967-02 NIGMS NIH HHS , R01 CA114197 NCI NIH HHS , R01 EY014576 NEI NIH HHS , R01 GM070967 NIGMS NIH HHS , R01 DK048796 NIDDK NIH HHS

Agulnik, Evolution of mouse T-box genes by tandem duplication and cluster dispersion. 1996, Pubmed

Agulnik, Evolution of mouse T-box genes by tandem duplication and cluster dispersion. 1996, Pubmed
Agulnik, Conservation of the T-box gene family from Mus musculus to Caenorhabditis elegans. 1995, Pubmed , Xenbase
Agulnik, Three novel T-box genes in Caenorhabditis elegans. 1997, Pubmed
Bamshad, Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome. 1997, Pubmed
Basson, Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome. 1997, Pubmed
Bollag, An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T locus. 1994, Pubmed
Bulfone, T-brain-1: a homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex. 1995, Pubmed
Call, Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. 1990, Pubmed
Campbell, Cloning and mapping of a human gene (TBX2) sharing a highly conserved protein motif with the Drosophila omb gene. 1995, Pubmed
Carreira, Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter. 1998, Pubmed
Chapman, Tbx6, a mouse T-Box gene implicated in paraxial mesoderm formation at gastrulation. 1996, Pubmed
Chapman, Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6. 1998, Pubmed
Chieffo, Isolation and characterization of a gene from the DiGeorge chromosomal region homologous to the mouse Tbx1 gene. 1997, Pubmed , Xenbase
Chow, The Rb family contains a conserved cyclin-dependent-kinase-regulated transcriptional repressor motif. 1996, Pubmed
Chow, Domains A and B in the Rb pocket interact to form a transcriptional repressor motif. 1996, Pubmed
Conlon, Effects of the TWis mutation on notochord formation and mesodermal patterning. 1995, Pubmed
Conlon, Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm. 1996, Pubmed , Xenbase
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Desplan, The Drosophila developmental gene, engrailed, encodes a sequence-specific DNA binding activity. , Pubmed
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Gessler, Homozygous inactivation of WT1 in a Wilms' tumor associated with the WAGR syndrome. 1993, Pubmed
Gessler, Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. 1990, Pubmed
Gibson-Brown, Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development. 1998, Pubmed
Gibson-Brown, Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity. 1996, Pubmed
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Griffin, Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genes. 1998, Pubmed , Xenbase
Grimm, Control of the gene optomotor-blind in Drosophila wing development by decapentaplegic and wingless. 1996, Pubmed
Guan, A point mutation within exon 5 of the WT1 gene of a sporadic unilateral Wilms' tumor alters gene function. 1998, Pubmed
Haber, An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor. 1990, Pubmed
Hagemeier, The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB. 1993, Pubmed
Halpern, Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation. 1993, Pubmed
Han, Functional domains of the Drosophila Engrailed protein. 1993, Pubmed
Han, Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain. 1993, Pubmed
Hanna-Rose, Two evolutionarily conserved repression domains in the Drosophila Kruppel protein differ in activator specificity. 1997, Pubmed
Herrmann, The T genes in embryogenesis. 1994, Pubmed , Xenbase
Herrmann, Cloning of the T gene required in mesoderm formation in the mouse. 1990, Pubmed
Herrmann, Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos. 1991, Pubmed
Holland, Conservation of Brachyury (T) genes in amphioxus and vertebrates: developmental and evolutionary implications. 1995, Pubmed
Horb, A vegetally localized T-box transcription factor in Xenopus eggs specifies mesoderm and endoderm and is essential for embryonic mesoderm formation. 1997, Pubmed , Xenbase
Horb, Tbx5 is essential for heart development. 1999, Pubmed , Xenbase
Hug, tbx6, a Brachyury-related gene expressed by ventral mesendodermal precursors in the zebrafish embryo. 1997, Pubmed
Ingham, Regulation of segment polarity genes in the Drosophila blastoderm by fushi tarazu and even skipped. 1988, Pubmed
Isaac, Tbx genes and limb identity in chick embryo development. 1998, Pubmed
Isaacs, eFGF regulates Xbra expression during Xenopus gastrulation. 1994, Pubmed , Xenbase
Jaynes, Active repression of transcription by the engrailed homeodomain protein. 1991, Pubmed
Johnson, The price of repression. 1995, Pubmed
Kispert, The T protein encoded by Brachyury is a tissue-specific transcription factor. 1995, Pubmed
Kispert, The chick Brachyury gene: developmental expression pattern and response to axial induction by localized activin. 1995, Pubmed , Xenbase
Kispert, The Brachyury gene encodes a novel DNA binding protein. 1993, Pubmed , Xenbase
Kispert, Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta. 1994, Pubmed
Knezevic, Two novel chick T-box genes related to mouse Brachyury are expressed in different, non-overlapping mesodermal domains during gastrulation. 1997, Pubmed
Kopp, Control of cell fate and polarity in the adult abdominal segments of Drosophila by optomotor-blind. 1997, Pubmed
Künzler, Functional differences between mammalian transcription activation domains at the yeast GAL1 promoter. 1994, Pubmed
Law, TBX10, a member of the Tbx1-subfamily of conserved developmental genes, is located at human chromosome 11q13 and proximal mouse chromosome 19. 1998, Pubmed
Law, Identification, characterization, and localization to chromosome 17q21-22 of the human TBX2 homolog, member of a conserved developmental gene family. 1995, Pubmed
Li, A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate. 1997, Pubmed , Xenbase
Li, Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family. 1997, Pubmed
Licht, Mapping and mutagenesis of the amino-terminal transcriptional repression domain of the Drosophila Krüppel protein. 1994, Pubmed
Licht, Drosophila Krüppel protein is a transcriptional repressor. 1990, Pubmed
Logan, Differential regulation of T-box and homeobox transcription factors suggests roles in controlling chick limb-type identity. 1998, Pubmed
Luo, Rb interacts with histone deacetylase to repress transcription. 1998, Pubmed
Lustig, Expression cloning of a Xenopus T-related gene (Xombi) involved in mesodermal patterning and blastopore lip formation. 1996, Pubmed , Xenbase
Macdonald, Isolation, structure, and expression of even-skipped: a second pair-rule gene of Drosophila containing a homeo box. 1986, Pubmed
Madden, Transcriptional repression mediated by the WT1 Wilms tumor gene product. 1991, Pubmed
Ohkuma, Binding site-dependent direct activation and repression of in vitro transcription by Drosophila homeodomain proteins. 1990, Pubmed
Ohuchi, Correlation of wing-leg identity in ectopic FGF-induced chimeric limbs with the differential expression of chick Tbx5 and Tbx4. 1998, Pubmed
Papaioannou, The T-box gene family. 1998, Pubmed , Xenbase
Pelletier, WT1 mutations contribute to abnormal genital system development and hereditary Wilms' tumour. 1991, Pubmed
Pelletier, Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome. 1991, Pubmed
Pflugfelder, The lethal(1)optomotor-blind gene of Drosophila melanogaster is a major organizer of optic lobe development: isolation and characterization of the gene. 1992, Pubmed
Pflugfelder, A homology domain shared between Drosophila optomotor-blind and mouse Brachyury is involved in DNA binding. 1992, Pubmed
Porsch, Isolation of a Drosophila T-box gene closely related to human TBX1. 1998, Pubmed
Ruvinsky, Characterization of the zebrafish tbx16 gene and evolution of the vertebrate T-box family. 1998, Pubmed , Xenbase
Ruvinsky, Newly identified paralogous groups on mouse chromosomes 5 and 11 reveal the age of a T-box cluster duplication. 1997, Pubmed
Ryan, Eomesodermin, a key early gene in Xenopus mesoderm differentiation. 1996, Pubmed , Xenbase
Sadowski, GAL4 fusion vectors for expression in yeast or mammalian cells. 1992, Pubmed
Schulte-Merker, The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo. 1992, Pubmed
Schulte-Merker, no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. 1994, Pubmed
Seipel, Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions. 1992, Pubmed
Simon, A novel family of T-box genes in urodele amphibian limb development and regeneration: candidate genes involved in vertebrate forelimb/hindlimb patterning. 1997, Pubmed
Smith, Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. 1991, Pubmed , Xenbase
Stennard, The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation. 1996, Pubmed , Xenbase
Stott, Rescue of the tail defect of Brachyury mice. 1993, Pubmed
Svaren, NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli. 1996, Pubmed
Wattler, A combined analysis of genomic and primary protein structure defines the phylogenetic relationship of new members if the T-box family. 1998, Pubmed
Weintraub, Mechanism of active transcriptional repression by the retinoblastoma protein. 1995, Pubmed
Wilkinson, Expression pattern of the mouse T gene and its role in mesoderm formation. 1990, Pubmed , Xenbase
Wilson, The T gene is necessary for normal mesodermal morphogenetic cell movements during gastrulation. 1995, Pubmed
Wilson, Chimeric analysis of T (Brachyury) gene function. 1993, Pubmed
Yasuo, An Ascidian Homolog of the Mouse Brachyury (T) Gene is Expressed Exclusively in Notochord Cells at the Fate Restricted Stage: (Ascidians/T (Brachyury) gene/sequence conservation/notochord cells/transient expression). 1994, Pubmed
Zhang, Xenopus VegT RNA is localized to the vegetal cortex during oogenesis and encodes a novel T-box transcription factor involved in mesodermal patterning. 1996, Pubmed , Xenbase
Zhang, The role of maternal VegT in establishing the primary germ layers in Xenopus embryos. 1998, Pubmed , Xenbase