Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Nucleic Acids Res
1999 Aug 01;2715:3146-52. doi: 10.1093/nar/27.15.3146.
Show Gene links
Show Anatomy links
Analysis of the chicken TBP-like protein(tlp) gene: evidence for a striking conservation of vertebrate TLPs and for a close relationship between vertebrate tbp and tlp genes.
Shimada M
,
Ohbayashi T
,
Ishida M
,
Nakadai T
,
Makino Y
,
Aoki T
,
Kawata T
,
Suzuki T
,
Matsuda Y
,
Tamura T
.
???displayArticle.abstract???
TLP (TBP-like protein), which is a new protein dis-covered by us, has a structure similar to that of the C-terminal conserved domain (CCD) of TBP, although its function has not yet been elucidated. We isolated cDNA and genomic DNA that encode chicken TLP (cTLP) and determined their structures. The predicted amino acid sequence of cTLP was 98 and 91% identical to that of its mammalian and Xenopus counterparts, respectively, and its translation product was ubiquitously observed in chicken tissues. FISH detection showed that chicken tlp and tbp genes were mapped at 3q2.6-2.8 and 3q2.4-2.6 of the same chromosome, respectively. Genome analysis revealed that the chicken tlp gene was spliced with five introns. Interestingly, the vertebrate tbp genes were also found to be split by five introns when we focused on the CCDs, and their splicing points were similar to those of tlp. On the contrary, another TBP-resembling gene of Drosophila, trf1, is split by only one intron, as is the Drosophila 's tbp gene. These results support our earlier assumption that vertebrate TLPs did not directly descend from Drosophila TRF1. On the basis of these results together with phylogenetical exam-ination, we speculate that tlp diverged from an ancestral tbp gene through a process of gene duplication and point mutations.
Baba,
Cell lines derived from avian lymphomas exhibit two distinct phenotypes.
1985, Pubmed
Baba,
Cell lines derived from avian lymphomas exhibit two distinct phenotypes.
1985,
Pubmed
Benoist,
In vivo sequence requirements of the SV40 early promotor region.
1981,
Pubmed
Buerstedde,
Light chain gene conversion continues at high rate in an ALV-induced cell line.
1990,
Pubmed
Chalut,
Genomic structure of the human TATA-box-binding protein (TBP).
1995,
Pubmed
Crowley,
A new factor related to TATA-binding protein has highly restricted expression patterns in Drosophila.
1993,
Pubmed
Gasch,
Arabidopsis thaliana contains two genes for TFIID.
1990,
Pubmed
Hancock,
Evolution of sequence repetition and gene duplications in the TATA-binding protein TBP (TFIID).
1993,
Pubmed
Hansen,
Transcription properties of a cell type-specific TATA-binding protein, TRF.
1997,
Pubmed
Hernandez,
TBP, a universal eukaryotic transcription factor?
1993,
Pubmed
Hoffmann,
Cloning of the Schizosaccharomyces pombe TFIID gene reveals a strong conservation of functional domains present in Saccharomyces cerevisiae TFIID.
1990,
Pubmed
Horikoshi,
Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box.
1989,
Pubmed
Imbert,
The gene for the TATA binding protein (TBP) that contains a highly polymorphic protein coding CAG repeat maps to 6q27.
1994,
Pubmed
Kao,
Cloning of a transcriptionally active human TATA binding factor.
1990,
Pubmed
Laemmli,
Cleavage of structural proteins during the assembly of the head of bacteriophage T4.
1970,
Pubmed
Lira-DeVito,
Structure of the genes encoding transcription factor IIB and TATA box-binding protein from Drosophila melanogaster.
1995,
Pubmed
Matsuda,
Location of the mouse complement factor H gene (cfh) by FISH analysis and replication R-banding.
1992,
Pubmed
Matsuda,
Application of fluorescence in situ hybridization in genome analysis of the mouse.
1995,
Pubmed
McKnight,
Transcriptional control signals of a eukaryotic protein-coding gene.
1982,
Pubmed
Muhich,
cDNA clone encoding Drosophila transcription factor TFIID.
1990,
Pubmed
Nakashima,
Structures of genes encoding TATA box-binding proteins from Trimeresurus gramineus and T. flavoviridis snakes.
1995,
Pubmed
Nikolov,
Crystal structure of TFIID TATA-box binding protein.
1992,
Pubmed
Ohbayashi,
Identification of a mouse TBP-like protein (TLP) distantly related to the drosophila TBP-related factor.
1999,
Pubmed
Ohbayashi,
Isolation of cDNA, chromosome mapping, and expression of the human TBP-like protein.
1999,
Pubmed
Page,
TreeView: an application to display phylogenetic trees on personal computers.
1996,
Pubmed
Perletti,
The TATA-binding protein and its associated factors are differentially expressed in adult mouse tissues.
1999,
Pubmed
Rabenstein,
TATA box-binding protein (TBP)-related factor 2 (TRF2), a third member of the TBP family.
1999,
Pubmed
Roeder,
The role of general initiation factors in transcription by RNA polymerase II.
1996,
Pubmed
Sharp,
TATA-binding protein is a classless factor.
1992,
Pubmed
Studier,
Use of T7 RNA polymerase to direct expression of cloned genes.
1990,
Pubmed
Sumita,
Structure of a mammalian TBP (TATA-binding protein) gene: isolation of the mouse TBP genome.
1993,
Pubmed
Tamura,
Striking homology of the 'variable' N-terminal as well as the 'conserved core' domains of the mouse and human TATA-factors (TFIID).
1991,
Pubmed
Thompson,
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
1994,
Pubmed
Vogel,
Expression of the two maize TATA binding protein genes and function of the encoded TBP proteins by complementation in yeast.
1993,
Pubmed
Yamamoto,
A bipartite DNA binding domain composed of direct repeats in the TATA box binding factor TFIID.
1992,
Pubmed
Yamauchi,
Two forms of avian(chicken) TATA-binding protein mRNA generated by alternative polyadenylation.
1997,
Pubmed
Yu,
Generation and functional analyses for base-substitution mutants of the adenovirus 2 major late promoter.
1984,
Pubmed
