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XB-ART-12789
J Am Vet Med Assoc. June 15, 1999; 214 (12): 1833-8, 1792-3.

Identification and management of an outbreak of Flavobacterium meningosepticum infection in a colony of South African clawed frogs (Xenopus laevis).

Green SL , Bouley DM , Tolwani RJ , Waggie KS , Lifland BD , Otto GM , Ferrell JE .


Abstract
During the summer of 1996, an outbreak of Flavobacterium meningosepticum infection developed in a colony of South African clawed frogs (Xenopus laevis). Clinical signs were consistent with septicemia: ascites, anasarca, dyspnea, extreme lethargy, congestion of web vessels, petechial hemorrhages, and sudden death. Mortality rate reached 35%, and all infections were fatal. The organism was resistant to most antibiotics but was susceptible to enrofloxacin, chloramphenicol, and trimethoprim-sulfadiazine. Treatment with trimethoprim-sulfadiazine was unsuccessful. Although the point source of the infection was not determined, several environmental reservoirs were identified, including a communal water barrel and various pieces of equipment. Molecular strain typing by pulsed-field gel electrophoresis and biochemical analyses revealed that frogs were infected with a single strain of F meningosepticum. Sanitation and management procedures were effective in controlling the outbreak.

PubMed ID: 10382028
Article link:
Grant support: GM46383 NIGMS NIH HHS , GM51233 NIGMS NIH HHS , PA95-049 PHS HHS

Genes referenced:
Antibodies referenced:
Morpholinos referenced:

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