XB-ART-13347
Dev Biol
1999 Feb 13;8182:565-9.
Show Gene links
Show Anatomy links
Nuclear localization of ciliary neurotrophic factor in glial cells.
???displayArticle.abstract???
In this work we studied the subcellular localization of ciliary neurotrophic factor (CNTF) in primary culture of rat cortical type I astrocytes and rat glioma C6 cells, transfected COS-7 cells and in the Xenopus oocytes. In all these models, morphological and biochemical evidence are provided for the nuclear localization of CNTF. In addition the nuclear translocation of CNTF is temperature-sensitive and thus strongly suggestive of a mechanism of facilitated transport.
???displayArticle.pubmedLink??? 10082849
???displayArticle.link??? Dev Biol
Species referenced: Xenopus
Genes referenced: cntf