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XB-ART-14258
Mech Dev July 1, 1998; 75 (1-2): 155-8.

Xenopus eomesodermin is expressed in neural differentiation.

Ryan K , Butler K , Bellefroid E , Gurdon JB .


Abstract
Our initial description of the Xenopus gene Eomesodermin (Eomes) indicated that it is expressed largely if not entirely in mesodermal cells of gastrula stage embryos. A more detailed examination, described here, shows that it continues to be expressed in the most anterior (future head) mesoderm during gastrula and neurula stages. However, during tail-bud stages, Eomes expression is re-born in the most anterior part of the brain, becoming strongly transcribed in the olfactory region of the telencephalon. This later Eomes expression marks a very localized region of the forebrain distinct from that of Otx-2, anterior to that of En-1 and overlapping that of Sox-3.

PubMed ID: 9739133
Article link: Mech Dev
Grant support: [+]
Genes referenced: en1 en2 eomes neurod1 otx2 sox3 tub tubb2b


Article Images: [+] show captions


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