XB-ART-16660Curr Biol April 1, 1997; 7 (4): R212-5.
Vertebrates have consistent differences between their left and right sides. In all species, nodal, a transforming growth factor beta superfamily signalling protein, is involved in a late step in the pathways that specify such asymmetry in the embryo. Earlier components seem not so well conserved.
PubMed ID: 9162493
Article link: Curr Biol
Genes referenced: acvr2a gdf1 lefty nodal shh snai1 tgfb1