Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-17064
FEBS Lett 1997 Jan 03;4002:183-7. doi: 10.1016/s0014-5793(96)01389-0.
Show Gene links Show Anatomy links

Structure and distribution of a broadly expressed atypical sodium channel.

Akopian AN , Souslova V , Sivilotti L , Wood JN .


???displayArticle.abstract???
A cDNA clone isolated from a rat dorsal root ganglion library encodes a 195 kDa voltage-gated sodium channel-like protein (SCL-11) with homology to the mouse (87%) and human (72%) atypical Na+ channels and rat partial clone NaG (98%). Two dominant mRNAs of 4.5 and 7 kb are expressed. The transcripts are present in lung, Schwann cells, pituitary and tissues containing smooth muscle cells. No functional channels could be detected on oocyte injection with cRNA, consistent with the absence of structural features necessary for voltage-gated sodium channel activity.

???displayArticle.pubmedLink??? 9001394
???displayArticle.link??? FEBS Lett
???displayArticle.grants??? [+]

Species referenced: Xenopus
Genes referenced: nbas