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Trends Genet December 1, 1996; 12 (12): 525-31.

The vertebrate organizer: structure and molecules.

Since the identification of the first organizer gene, goosecoid, more than 15 organizer-specific genes have been characterized. Here, we present our current understanding of the roles of these molecules in amphibians fish and amniotes and show how there identification has confirmed Spemann''s original proposition that the vertebrate organizer is subdivided into separate domains: the head, trunk and tail organizers.

PubMed ID: 9257536
Article link: Trends Genet

Species referenced: Xenopus laevis
Genes referenced: gsc gsc2