Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Bioessays September 1, 1996; 18 (9): 701-4.

The coming of age of ventralising homeobox genes in amphibian development.

The emerging view of early dorso-ventral patterning of amphibian embryos is that two opposing gradients of dorsalising and ventralising secreted factors are necessary. While several transcription factors acting upstream or downstream of the dorsalising molecules have been identified, until recently little was known about the transcriptional response to ventralising signals. Now two groups describe the identification of related homeodomain proteins, Xvent-1 and Vox, which are able to convert dorsal cells of Xenopus embryos into more ventral ones.

PubMed ID: 8831285
Article link: Bioessays

Genes referenced: ventx1.2 ventx2.1

Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556