Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Dev Biol December 1, 1995; 172 (2): 699-703.

A novel TGF-beta-like gene, fugacin, specifically expressed in the Spemann organizer of Xenopus.

Ecochard V , Cayrol C , Foulquier F , Zaraisky A , Duprat AM .

Using a differential screening strategy, we have cloned a novel Xenopus gene, fugacin, related to the transforming growth factor beta superfamily. Transcripts were detected primarily in the dorsal marginal zone of late blastula. Thereafter, they became highly localized to the blastopore lip of early gastrula and were not observed at later stages. This gene, which is most homologous to the mouse gene nodal, displays a new pattern of cysteine residues. These findings highlight the potential role of these growth factors during early vertebrate development.

PubMed ID: 8612984
Article link: Dev Biol

Genes referenced: nodal nodal1 nodal3.1 nodal3.2 nodal3.3 nodal3.4 tgfb1

Article Images: [+] show captions

Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556