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XB-ART-20448
Science 1992 Dec 04;2585088:1654-8.
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Expression of an inward-rectifying potassium channel by the Arabidopsis KAT1 cDNA.

Schachtman DP , Schroeder JI , Lucas WJ , Anderson JA , Gaber RF .


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Inward-rectifying potassium channels located in the plasma membrane of higher plant and animal cells contribute to cellular homeostasis and excitability. The genes encoding this specific class of K+ channels have not been functionally identified. This report shows that a single messenger RNA transcript from the Arabidopsis thaliana KAT1 complementary DNA confers the functional expression of a hyperpolarization-activated K+ channel in Xenopus oocytes. The channels encoded by KAT1 are highly selective for K+ over other monovalent cations, are blocked by tetraethylammonium and barium, and have a single channel conductance of 28 +/- 7 picosiemens with 118 millimolar K+ in the bathing solution. These functional characteristics, typical of inward-rectifying K+ channels in eukaryotic cells, demonstrate that KAT1 encodes an inward-rectifying K+ channel.

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Species referenced: Xenopus
Genes referenced: kyat1