XB-ART-2269
Differentiation
2005 Feb 01;731:1-17. doi: 10.1111/j.1432-0436.2005.07301005.x.
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How to make an egg: transcriptional regulation in oocytes.
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The oocyte is a highly differentiated cell. It makes organelles specialized to its unique functions and progresses through a series of developmental stages to acquire a fertilization competent phenotype. This review will integrate the biology of the oocyte with what is known about oocyte-specific gene regulation and transcription factors involved in oocyte development. We propose that oogenesis is reliant on a dynamic gene regulatory network that includes oocyte-specific transcriptional regulators.
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