Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-22925
Science 1993 Jan 08;2595092:244-6.
Show Gene links Show Anatomy links

Forward plasma membrane flow in growing nerve processes.

Popov S , Brown A , Poo MM .


???displayArticle.abstract???
Nerve growth requires addition of new plasma membrane material, which is generally believed to occur at the growth cone. Local incorporation of a fluorescent lipid analog into the plasma membrane of fast-growing Xenopus neurites revealed an anterograde bulk membrane flow that correlated with neurite elongation. The rate of membrane flow depended on the position of the labeled membrane segment along the neurite, increasing with distance from the soma. This result suggests that new membrane in growing Xenopus neurites is added not at the growth cone but at the cell body and along the neurite.

???displayArticle.pubmedLink??? 7678471
???displayArticle.link??? Science
???displayArticle.grants??? [+]