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XB-ART-23719
FEBS Lett May 25, 1992; 303 (1): 81-4.

Multiple genes for Xenopus activin receptor expressed during early embryogenesis.

Nishimatsu S , Oda S , Murakami K , Ueno N .


Abstract
Four distinct cDNAs for activin receptor designated as XSTK2, 3, 8 and 9 have been cloned from a Xenopus laevis cDNA library. The protein structures deduced from the cDNAs have shown that they all have a putative extracellular ligand-binding domain, a single transmembrane domain and cytoplasmic Ser/Thr kinase domain, except that XSTK2 is extremely similar to the XSTK3 gene but lacks a carboxyl-terminal part of the kinase motif. Northern blot analysis showed that all transcripts are maternally inherited. The levels of transcript for XSTK2, 3 and 8 appeared to fluctuate during early development while those for XSTK9 maintain constant.

PubMed ID: 1317302
Article link:


Species referenced: Xenopus laevis
Genes referenced: acvr2a cdkl5 stk3