Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-24414
Cell Calcium November 1, 1991; 12 (10): 683-93.

Neural regulation of calmodulin in adult Xenopus leg muscle.

Nishikawa BK , Kay BK .


Abstract
Two Ca(2+)-binding proteins important in regulating muscle responses to Ca2+ flux are differentially expressed following denervation of Xenopus laevis gastrocnemius. Levels of parvalbumin (PV) RNA transcripts and proteins decrease in abundance, while calmodulin (CaM) transcript and protein levels increase. Our studies on PV kinetics in Xenopus follow a pattern observed in other species, however, our observation of a concomitant increase in CaM has not been documented in any system. Molecular analyses of the Xenopus CaM gene indicate that its structure and upstream sequences are highly conserved across several vertebrate species and implicate several transcription factors in the regulation of its expression.

PubMed ID: 1769061
Article link:
Grant support: [+]
Genes referenced: ocm3 ocm4.5



Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.3


Major funding for Xenbase is provided by grant P41 HD064556