XB-ART-24761Biochim Biophys Acta June 13, 1991; 1089 (2): 280-2.
Screening of a Xenopus laevis ovary cDNA library with an oligonucleotide derived from the activin A sequence led to the isolation of several clones belonging to the TGF-beta supergene family. One of these clones codes for the Xenopus bone morphogenetic protein 2 (BMP-2). The deduced protein contains 398 amino acids with a predicted Mr of 45,581. Within the C-terminal 114 amino acids constituting the mature, biologically active protein there are only four exchanges (three of them are conservative ones) as compared to the corresponding human sequence.
PubMed ID: 2054389
Article link: Biochim Biophys Acta
Genes referenced: bmp2