XB-ART-24975
Biochem Biophys Res Commun
1991 Mar 29;1753:1036-41.
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Xenopus transcription factor IIIC (TFIIIC) specifically interacts with the "B" block region of the TFIIIA gene.
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Transcription factors IIIC (TFIIIC), TFIIIB and RNA polymerase III are commonly required for class III gene transcription in vitro. To understand the diversity and specificity of Xenopus TFIIIC, we have further characterized this factor. Our analyses indicate that a partially purified TFIIIC fraction contains an activity which specifically recognizes the "B" block element of TFIIIA gene. Stable complex formation assays with HeLa cell extracts demonstrate that the TFIIIA gene can stably sequester TFIIIC. off
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Species referenced: Xenopus laevis
Genes referenced: bdp1 gtf3a gtf3c1