Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Anat Embryol (Berl)
1990 Jan 01;1821:53-67. doi: 10.1007/bf00187527.
Show Gene links
Show Anatomy links
Origin and distribution of enteric neurones in Xenopus.
Epperlein HH
,
Krotoski D
,
Halfter W
,
Frey A
.
???displayArticle.abstract???
In Xenopus, we investigated the origin of enteric neurones and their distribution in relation to the extracellular matrix (ECM) components, fibronectin (FN) and tenascin (TN). Enteric neurone precursor cells originate from the anteriortrunk neural crest (NC). They migrate along the ventromedial NC pathway (between somites and neural tube/notochord) into the primitive gut (via the dorsal mesentery/lateral plate mesoderm) where they differentiate into enteric neurones. NC cells were identified during their migration and in the gut using the X. laevis - X. borealis nuclear marker system. The neuronal character of NC cells in the gut could be demonstrated immunohistochemically with a monoclonal antibody against the HNK-1 epitope. This antibody is superior to N-CAM and neurofilament antibodies which proved insufficient in Xenopus. In early tadpoles (stage 45), enteric neurones occurred frequently in the mesenchymal lining of the oesophagus, either singly or in groups of two to three cells. In more distal portions of the digestive tract, enteric neurones were rarely found. In metamorphosing tadpoles (stage 62/63), enteric neurones were scattered singly beneath the mucosa, or formed small aggregates between the inner and outer muscle layer throughout the length of the digestive tract. The neurones occurred in positions corresponding to the myenteric and submucosal plexus of higher vertebrates. The distribution of enteric neurones was studied in relation to fibronectin (FN) and tenascin (TN), glycoproteins of the ECM, which support (FN) and inhibit (TN) amphibian NC cell migration. Using immunohistochemistry, FN was found during NC cell migration in ECM spaces along the ventromedial pathway, and in the gut between the mucosa and the muscle layers, where it would be able to support adhesion and migration of NC cells. TN, in contrast, appeared much later than FN, both in the dorsal trunk and also ventrally, in the gut. In older tadpoles, TN was present in the mesenchyme and muscle layers of the digestive tract, where it might have an inhibiting influence on the migration of enteric neurones within the gut wall.
Allan,
The origin and differentiation of enteric neurons of the intestine of the fowl embryo.
1980, Pubmed
Allan,
The origin and differentiation of enteric neurons of the intestine of the fowl embryo.
1980,
Pubmed
Andrew,
The origin of intramural ganglia. IV. The origin of enteric ganglia: a critical review and discussion of the present state of the problem.
1971,
Pubmed
Aufderheide,
Tenascin during gut development: appearance in the mesenchyme, shift in molecular forms, and dependence on epithelial-mesenchymal interactions.
1988,
Pubmed
Boucaut,
Biologically active synthetic peptides as probes of embryonic development: a competitive peptide inhibitor of fibronectin function inhibits gastrulation in amphibian embryos and neural crest cell migration in avian embryos.
1984,
Pubmed
Bronner-Fraser,
Analysis of the early stages of trunk neural crest migration in avian embryos using monoclonal antibody HNK-1.
1986,
Pubmed
Bronner-Fraser,
Distribution and function of tenascin during cranial neural crest development in the chick.
1988,
Pubmed
Burnstock,
Autonomic neuromuscular junctions: current developments and future directions.
1986,
Pubmed
Chiquet-Ehrismann,
Tenascin interferes with fibronectin action.
1988,
Pubmed
Chiquet-Ehrismann,
Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis.
1986,
Pubmed
Ciment,
Enteric neurogenesis by neural crest-derived branchial arch mesenchymal cells.
,
Pubmed
Epperlein,
The distribution of fibronectin and tenascin along migratory pathways of the neural crest in the trunk of amphibian embryos.
1988,
Pubmed
,
Xenbase
Fox,
Aspects of the ultrastructure of the alimentary canal and associated glands of the Xenopus laevis larva.
1970,
Pubmed
,
Xenbase
Fox,
Aspects of the ultrastructure of the alimentary canal and respiratory ducts in Xenopus laevis larvae.
1972,
Pubmed
,
Xenbase
GUNN,
A study of the enteric plexuses in some amphibians.
1951,
Pubmed
Gabella,
Innervation of the gastrointestinal tract.
1979,
Pubmed
Gershon,
The enteric nervous system.
1981,
Pubmed
Greenberg,
Role of collagen and fibronectin in neural crest cell adhesion and migration.
1981,
Pubmed
Halfter,
The effect of tenascin and embryonic basal lamina on the behavior and morphology of neural crest cells in vitro.
1989,
Pubmed
Ishizuya-Oka,
Ultrastructural changes in the intestinal connective tissue of Xenopus laevis during metamorphosis.
1987,
Pubmed
,
Xenbase
Ishizuya-Oka,
Development of the connective tissue in the digestive tract of the larval and metamorphosing Xenopus laevis.
1987,
Pubmed
,
Xenbase
KEMP,
Development of intestinal coiling in anuran larvae.
1951,
Pubmed
Kordylewski,
Light and electron microscopic observations of the development of intestinal musculature in Xenopus.
1983,
Pubmed
,
Xenbase
Krotoski,
Distribution of a putative cell surface receptor for fibronectin and laminin in the avian embryo.
1986,
Pubmed
Krotoski,
Mapping of neural crest pathways in Xenopus laevis using inter- and intra-specific cell markers.
1988,
Pubmed
,
Xenbase
Lander,
Laminin is associated with the "neurite outgrowth-promoting factors" found in conditioned media.
1985,
Pubmed
Le Douarin,
[Details of the interphase nucleus in Japanese quail (Coturnix coturnix japonica)].
1969,
Pubmed
Le Douarin,
The migration of neural crest cells to the wall of the digestive tract in avian embryo.
1973,
Pubmed
Le Douarin,
Experimental analysis of the migration and differentiation of neuroblasts of the autonomic nervous system and of neurectodermal mesenchymal derivatives, using a biological cell marking technique.
1974,
Pubmed
Mackie,
The distribution of tenascin coincides with pathways of neural crest cell migration.
1988,
Pubmed
,
Xenbase
Macmillan,
Melanoblast-tissue interactions and the development of pigment pattern in Xenopus larvae.
1976,
Pubmed
,
Xenbase
Newgreen,
The migration of neural crest cells.
1986,
Pubmed
Newgreen,
Ultrastructural and tissue-culture studies on the role of fibronectin, collagen and glycosaminoglycans in the migration of neural crest cells in the fowl embryo.
1982,
Pubmed
Nordlander,
HNK-1 marks earliest axonal outgrowth in Xenopus.
1989,
Pubmed
,
Xenbase
Perris,
Local embryonic matrices determine region-specific phenotypes in neural crest cells.
1988,
Pubmed
Rovasio,
Neural crest cell migration: requirements for exogenous fibronectin and high cell density.
1983,
Pubmed
Sadaghiani,
Neural crest development in the Xenopus laevis embryo, studied by interspecific transplantation and scanning electron microscopy.
1987,
Pubmed
,
Xenbase
Stern,
J1/tenascin-related molecules are not responsible for the segmented pattern of neural crest cells or motor axons in the chick embryo.
1989,
Pubmed
Tan,
Asymmetric expression in somites of cytotactin and its proteoglycan ligand is correlated with neural crest cell distribution.
1987,
Pubmed
Tennyson,
Abnormalities of smooth muscle, basal laminae, and nerves in the aganglionic segments of the bowel of lethal spotted mutant mice.
1986,
Pubmed
Thiery,
Cell migration in the vertebrate embryo: role of cell adhesion and tissue environment in pattern formation.
1985,
Pubmed
Thiébaud,
A reliable new cell marker in Xenopus.
1983,
Pubmed
,
Xenbase
Tucker,
Identical reactivity of monoclonal antibodies HNK-1 and NC-1: conservation in vertebrates on cells derived from the neural primordium and on some leukocytes.
1984,
Pubmed
Tucker,
The control of pigment cell pattern formation in the California newt, Taricha torosa.
1986,
Pubmed
Tucker,
Expression of the HNK-1/NC-1 epitope in early vertebrate neurogenesis.
1988,
Pubmed
,
Xenbase
Tucker,
Pathways of avian neural crest cell migration in the developing gut.
1986,
Pubmed
Tucker,
The role of glycosaminoglycans in anuran pigment cell migration.
1986,
Pubmed
,
Xenbase
Vincent,
A cell surface marker for neural crest and placodal cells: further evolution in peripheral and central nervous system.
1984,
Pubmed
Vogel,
Development of the sympathetic system in the Mexican axolotl, Ambystoma mexicanum.
1977,
Pubmed
Wittekind,
A simple and reproducible staining procedure to assess characteristic effects of some fixatives.
1987,
Pubmed
