XB-ART-26325Nature December 7, 1989; 342 (6250): 643-8.
Cloning by functional expression of a member of the glutamate receptor family.
We have isolated a complementary DNA clone by screening a rat brain cDNA library for expression of kainate-gated ion channels in Xenopus oocytes. The cDNA encodes a single protein of relative molecular mass (Mr) 99,800 which on expression in oocytes forms a functional ion channel possessing the electrophysiological and pharmacological properties of the kainate subtype of the glutamate receptor family in the mammalian central nervous system.
PubMed ID: 2480522
Article link: Nature