Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-28506
Cell 1986 Oct 24;472:217-27.
Show Gene links Show Anatomy links

DNA replication in vitro erases a Xenopus 5S RNA gene transcription complex.

Wolffe AP , Brown DD .


???displayArticle.abstract???
Replication of the Xenopus laevis 5S RNA gene in vitro is unimpeded by the presence of a complete transcription complex assembled on the internal control region of the gene. The transcription complex is disrupted by passage of the replication fork, specific transcription factors are displaced, and the daughter 5S RNA genes are inactivated. We have been unable to demonstrate that any "memory" of the preexisting transcription complex is transmitted to the daughter DNA duplexes following replication.

???displayArticle.pubmedLink??? 3021334
???displayArticle.link??? Cell