XB-ART-2945
Opt Lett
2004 Sep 01;2917:2016-8. doi: 10.1364/ol.29.002016.
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Spectral triangulation molecular contrast optical coherence tomography with indocyanine green as the contrast agent.
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We report a new molecular contrast optical coherence tomography (MCOCT) implementation that profiles the contrast agent distribution in a sample by measuring the agent's spectral differential absorption. The method, spectra triangulation MCOCT, can effectively suppress contributions from spectrally dependent scatterings from the sample without a priori knowledge of the scattering properties. We demonstrate molecular imaging with this new MCOCT modality by mapping the distribution of indocyanine green, a FDA-approved infrared red dye, within a stage 54 Xenopus laevis.
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2003, Pubmed