Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-29687
Science 1984 Jun 22;2244655:1343-6.
Show Gene links Show Anatomy links

Adenovirus E1a gene product expressed at high levels in Escherichia coli is functional.

Ferguson B , Jones N , Richter J , Rosenberg M .


???displayArticle.abstract???
The human type C adenovirus E1a 13S messenger RNA encodes a gene product, that positively regulates the transcription of viral genes and certain cellular genes and is involved in the transformation of primary mammalian cells. The E1a gene product was expressed at high levels in Escherichia coli. In a Xenopus oocyte microinjection assay, the purified Escherichia coli-produced protein activated the E1a-responsive adenovirus E3 promoter and functioned as efficiently as the E1a gene itself.

???displayArticle.pubmedLink??? 6374895
???displayArticle.link??? Science


Species referenced: Xenopus
Genes referenced: mst1