Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-29827
Nature February 16, 1984; 307 (5952): 604-8.

Expression of functional acetylcholine receptor from cloned cDNAs.

Mishina M , Kurosaki T , Tobimatsu T , Morimoto Y , Noda M , Yamamoto T , Terao M , Lindstrom J , Takahashi T , Kuno M .


Abstract
The cloned cDNAs encoding the four subunits of the Torpedo californica acetylcholine receptor, each carried by a simian virus 40 vector, direct the synthesis of the functional receptor in a combined expression system consisting of COS monkey cells and Xenopus oocytes. Our results suggest that all four subunits are required to elicit a normal nicotinic response to acetylcholine, whereas only the alpha-subunit is indispensable for alpha-bungarotoxin binding activity.

PubMed ID: 6320016
Article link:



Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.1


Major funding for Xenbase is provided by grant P41 HD064556