Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Independently evolving chicken histone H2B genes: identification of a ubiquitous H2B-specific 5' element.
Harvey RP
,
Robins AJ
,
Wells JR
.
???displayArticle.abstract???
The DNA sequence of two chicken histone H2B genes has been determined. Both genes code for the same H2B subtype. Except for conserved "promoter" elements, the sequences 5' to the protein coding regions are completely divergent, indicating that the genes are distantly related and are not evolving in concert. This presents an ideal situation for sequence comparisons. We have discovered a 13 bp, H2B specific homology block, 5' CTCATTTGCATAC 3' located close to the "TATA box". This motif is conserved in all H2B gene leader regions so far sequenced. One of the H2B genes is closely linked, in a divergent arrangement, to an H2A gene, and sequence data suggests that the linked genes share promoter elements.
Baltimore,
Gene conversion: some implications for immunoglobulin genes.
1981, Pubmed
Baltimore,
Gene conversion: some implications for immunoglobulin genes.
1981,
Pubmed
Birchmeier,
Generation of authentic 3' termini of an H2A mRNA in vivo is dependent on a short inverted DNA repeat and on spacer sequences.
1982,
Pubmed
Busslinger,
Ubiquitous and gene-specific regulatory 5' sequences in a sea urchin histone DNA clone coding for histone protein variants.
1980,
Pubmed
D'Andrea,
Vertebrate histone genes: nucleotide sequence of a chicken H2A gene and regulatory flanking sequences.
1981,
Pubmed
Efstratiadis,
The structure and evolution of the human beta-globin gene family.
1980,
Pubmed
Engel,
A chicken histone H3 gene contains intervening sequences.
1982,
Pubmed
Grosschedl,
Spacer DNA sequences upstream of the T-A-T-A-A-A-T-A sequence are essential for promotion of H2A histone gene transcription in vivo.
1980,
Pubmed
,
Xenbase
Grosschedl,
Delimitation of far upstream sequences required for maximal in vitro transcription of an H2A histone gene.
1982,
Pubmed
Heintz,
The structure of the human histone genes: clustered but not tandemly repeated.
1981,
Pubmed
Hentschel,
Sea urchin histone mRNA termini are located in gene regions downstream from putative regulatory sequences.
1980,
Pubmed
Hentschel,
The organization and expression of histone gene families.
1981,
Pubmed
Jones,
Structure, organization and evolution of developmentally regulated chorion genes in a silkmoth.
1980,
Pubmed
Kedes,
Histone genes and histone messengers.
1979,
Pubmed
Keene,
DNase I hypersensitive sites in Drosophila chromatin occur at the 5' ends of regions of transcription.
1981,
Pubmed
Lifton,
The organization of the histone genes in Drosophila melanogaster: functional and evolutionary implications.
1978,
Pubmed
Maxam,
Sequencing end-labeled DNA with base-specific chemical cleavages.
1980,
Pubmed
McKnight,
Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: identification of an upstream control region.
1981,
Pubmed
,
Xenbase
Moschonas,
The DNA sequence of the 5' flanking region of the human beta-globin gene: evolutionary conservation and polymorphic differences.
1982,
Pubmed
Platt,
Termination of transcription and its regulation in the tryptophan operon of E. coli.
1981,
Pubmed
Sanger,
DNA sequencing with chain-terminating inhibitors.
1977,
Pubmed
Shinagawa,
Inhibition of a nuclease contaminant in the commercial preparations of Escherichia coli alkaline phosphatase.
1979,
Pubmed
Sures,
The DNA sequence of sea urchin (S. purpuratus) H2A, H2B and H3 histone coding and spacer regions.
1978,
Pubmed
Urban,
Isolation and characterization of the histone variants in chicken erythrocytes.
1979,
Pubmed
Van Helden,
Histone H2B variants from the erythrocytes of an amphibian, a reptile and a bird.
1978,
Pubmed
,
Xenbase
Von Holt,
More histone structures.
1979,
Pubmed
