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XB-ART-37911
Neuron 2008 Jun 12;585:653-5. doi: 10.1016/j.neuron.2008.06.001.
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Seeing the light: insulin receptors and the CNS.

Needleman LA , McAllister AK .


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Although insulin clearly affects brain function, the role of insulin receptor (IR) signaling in the establishment and function of circuits in vivo remains largely unknown. In this issue of Neuron, Chiu et al. show a role for IRs in regulating synapse density and dendritic plasticity required for visual responses in Xenopus.

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Species referenced: Xenopus
Genes referenced: ins tbx2

References :
Chiu, Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo. 2008, Pubmed, Xenbase