XB-ART-38439Cell. September 5, 2008; 134 (5): 722-3.
Highways for mRNA transport.
Two new studies reveal the role of microtubule polarity in the asymmetric localization of mRNAs. In this issue of Cell, Zimyanin et al. (2008) show that the asymmetric localization of oskar mRNA in fruit fly oocytes results from a slight bias in the direction of its transport. Meanwhile, Messitt et al. (2008) reporting in Developmental Cell find a subpopulation of microtubules that is critical for the asymmetric distribution of Vg1 mRNA in frog oocytes.
PubMed ID: 18775304
PMC ID: PMC3148588
Article link: Cell.
Grant support: R01 GM084364-15A1 NIGMS NIH HHS , R01 GM084364-16 NIGMS NIH HHS , R01 GM084364-17 NIGMS NIH HHS , R01 GM084364-18 NIGMS NIH HHS
Genes referenced: gdf1