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XB-ART-41753
J Chem Ecol August 1, 2010; 36 (8): 797-800.

Odorant receptor from the southern house mosquito narrowly tuned to the oviposition attractant skatole.

Hughes DT , Pelletier J , Luetje CW , Leal WS .


Abstract
Oviposition attractants are environmental cues that allow Culex gravid female mosquitoes to locate suitable sites for egg-laying and, therefore, may be exploited for environmentally friendly strategies for controlling mosquito populations. Naturally occurring skatole has been identified as an oviposition attractant for the Southern House mosquito, Culex quinquefasciatus. Previously, we identified in Cx. quinquefasciatus female antennae an olfactory receptor neuron (ORN) highly sensitive to skatole and an odorant-binding protein involved in the detection of this semiochemical. Here, we describe the characterization of an odorant receptor (OR), CquiOR10, which is narrowly tuned to skatole when expressed in the Xenopus oocyte system. Odorant-induced response profiles generated by heterologously expressed CquiOR10 suggest that this OR is expressed in the mosquito ORN sensitive to skatole. However, geranylacetone, which stimulates the antennal ORN, was not detected by CquiOR10-expressing oocytes, thus raising interesting questions about reception of oviposition attractants in mosquitoes.

PubMed ID: 20623327
PMC ID: PMC2908433
Article link: J Chem Ecol
Grant support: [+]


Article Images: [+] show captions
References [+] :
Barbosa, Culex mosquitoes (Diptera: Culicidae) egg laying in traps loaded with Bacillus thuringiensis variety israelensis and baited with skatole. 2010, Pubmed


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