XB-ART-41933
Dev Cell
August 17, 2010;
19
(2):
190-2.
On the fast track to organizer gene expression.
Abstract
Many embryonic species are initially transcriptionally quiescent after fertilization. In this issue of Developmental Cell, Blythe et al. reveal that beta-catenin acts very early in Xenopus development to specifically modify the chromatin of organizer genes, poising them for rapid activation when transcription begins.
PubMed ID: 20708581
PMC ID: PMC5568668
Article link: Dev Cell
Grant support:
Genes referenced: nodal5 nodal6 tbx2
References [+] :
Belenkaya, pygopus Encodes a nuclear protein essential for wingless/Wnt signaling. 2002, Pubmed,
Xenbase
