XB-ART-41933
Dev Cell
August 17, 2010;
19
(2):
190-2.
On the fast track to organizer gene expression.
Abstract
Many embryonic species are initially transcriptionally quiescent after fertilization. In this issue of Developmental Cell, Blythe et al. reveal that beta-catenin acts very early in Xenopus development to specifically modify the chromatin of
organizer genes, poising them for rapid activation when transcription begins.
PubMed ID:
20708581
PMC ID:
PMC5568668
Article link:
Dev Cell
Grant support:
[+]
Species referenced:
Xenopus laevis
Genes referenced:
nodal5
nodal6
tbx2
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