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XB-ART-43196
J Physiol July 1, 2011; 589 (Pt 13): 3071-83.

A conserved tryptophan at the membrane-water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated.

Männikkö R , Stansfeld PJ , Ashcroft AS , Hattersley AT , Sansom MS , Ellard S , Ashcroft FM .


Abstract


PubMed ID: 21540348
PMC ID: PMC3145925
Article link: J Physiol
Grant support: [+]
Genes referenced: abcc8 kcnj11

References:
Aguilar-Bryan, 1995, Pubmed [+]


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