Berlin S , Tsemakhovich VA , Castel R , Ivanina T , Dessauer CW , Keren-Raifman T , Dascal N .

GM60419 NIGMS NIH HHS , R01 GM060419 NIGMS NIH HHS

Berlin, G alpha(i) and G betagamma jointly regulate the conformations of a G betagamma effector, the neuronal G protein-activated K+ channel (GIRK). 2010, Pubmed, Xenbase

Berlin, G alpha(i) and G betagamma jointly regulate the conformations of a G betagamma effector, the neuronal G protein-activated K+ channel (GIRK). 2010, Pubmed , Xenbase
Bykova, Large movement in the C terminus of CLC-0 chloride channel during slow gating. 2006, Pubmed
Bünemann, Gi protein activation in intact cells involves subunit rearrangement rather than dissociation. 2003, Pubmed
Chan, Specific regions of heteromeric subunits involved in enhancement of G protein-gated K+ channel activity. 1997, Pubmed , Xenbase
Clancy, Pertussis-toxin-sensitive Galpha subunits selectively bind to C-terminal domain of neuronal GIRK channels: evidence for a heterotrimeric G-protein-channel complex. 2005, Pubmed , Xenbase
Corey, The Stoichiometry of Gbeta gamma binding to G-protein-regulated inwardly rectifying K+ channels (GIRKs). 2001, Pubmed
Dascal, Ion-channel regulation by G proteins. 2001, Pubmed
Dascal, Atrial G protein-activated K+ channel: expression cloning and molecular properties. 1993, Pubmed , Xenbase
Dascal, Signalling via the G protein-activated K+ channels. 1997, Pubmed
Falkenburger, Kinetics of PIP2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells. 2010, Pubmed
Finley, betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation. 2004, Pubmed , Xenbase
Fowler, Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins. 2007, Pubmed
Galés, Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes. 2006, Pubmed
Gibson, Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors. 2006, Pubmed
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Huang, Evidence that direct binding of G beta gamma to the GIRK1 G protein-gated inwardly rectifying K+ channel is important for channel activation. 1995, Pubmed , Xenbase
Hébert, Detecting and imaging protein-protein interactions during G protein-mediated signal transduction in vivo and in situ by using fluorescence-based techniques. 2006, Pubmed
Ikeda, Voltage-dependent modulation of N-type calcium channels by G-protein beta gamma subunits. 1996, Pubmed
Ivanina, Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel. 2004, Pubmed , Xenbase
Ivanina, Expression of GIRK (Kir3.1/Kir3.4) channels in mouse fibroblast cells with and without beta1 integrins. 2000, Pubmed
Ivanina, Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel. 2003, Pubmed , Xenbase
Ivanova-Nikolova, Effector contributions to G beta gamma-mediated signaling as revealed by muscarinic potassium channel gating. 1997, Pubmed
James, A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer. 2006, Pubmed
Janetopoulos, Receptor-mediated activation of heterotrimeric G-proteins in living cells. 2001, Pubmed
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Kunkel, Identification of domains conferring G protein regulation on inward rectifier potassium channels. 1995, Pubmed , Xenbase
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Leal-Pinto, Gating of a G protein-sensitive mammalian Kir3.1 prokaryotic Kir channel chimera in planar lipid bilayers. 2010, Pubmed , Xenbase
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Logothetis, The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart. , Pubmed
Lüscher, Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease. 2010, Pubmed
Milligan, Heterotrimeric G-proteins: a short history. 2006, Pubmed
Mirshahi, Molecular determinants responsible for differential cellular distribution of G protein-gated inwardly rectifying K+ channels. 2004, Pubmed , Xenbase
Oldham, Heterotrimeric G protein activation by G-protein-coupled receptors. 2008, Pubmed
Peleg, G(alpha)(i) controls the gating of the G protein-activated K(+) channel, GIRK. 2002, Pubmed , Xenbase
Rebois, Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells. 2006, Pubmed , Xenbase
Rishal, Gbetagamma-dependent and Gbetagamma-independent basal activity of G protein-activated K+ channels. 2005, Pubmed , Xenbase
Rishal, Na+ promotes the dissociation between Galpha GDP and Gbeta gamma, activating G protein-gated K+ channels. 2003, Pubmed , Xenbase
Riven, GIRK channel activation involves a local rearrangement of a preformed G protein channel complex. 2006, Pubmed
Rubinstein, Galphai3 primes the G protein-activated K+ channels for activation by coexpressed Gbetagamma in intact Xenopus oocytes. 2007, Pubmed , Xenbase
Rubinstein, Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GalphaiGDP and Gbetagamma. 2009, Pubmed , Xenbase
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Sharon, Positive and negative coupling of the metabotropic glutamate receptors to a G protein-activated K+ channel, GIRK, in Xenopus oocytes. 1997, Pubmed , Xenbase
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Vorobiov, Coupling of the muscarinic m2 receptor to G protein-activated K(+) channels via Galpha(z) and a receptor-Galpha(z) fusion protein. Fusion between the receptor and Galpha(z) eliminates catalytic (collision) coupling. 2000, Pubmed , Xenbase
Waldhoer, Kinetics of ternary complex formation with fusion proteins composed of the A(1)-adenosine receptor and G protein alpha-subunits. 1999, Pubmed
Wang, Evidence for a second, high affinity Gbetagamma binding site on Galphai1(GDP) subunits. 2009, Pubmed
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Yamada, GK* and brain G beta gamma activate muscarinic K+ channel through the same mechanism. 1993, Pubmed
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Yevenes, Molecular requirements for ethanol differential allosteric modulation of glycine receptors based on selective Gbetagamma modulation. 2010, Pubmed
Zheng, Disruption of an intersubunit interaction underlies Ca2+-calmodulin modulation of cyclic nucleotide-gated channels. 2003, Pubmed , Xenbase
Zheng, Patch-clamp fluorometry recording of conformational rearrangements of ion channels. 2003, Pubmed , Xenbase
Zylbergold, The role of G proteins in assembly and function of Kir3 inwardly rectifying potassium channels. 2010, Pubmed