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Dev Dyn June 1, 2009; 238 (6): 1613-6.

Expression of stem cell pluripotency factors during regeneration in newts.

Maki N , Suetsugu-Maki R , Tarui H , Agata K , Del Rio-Tsonis K , Tsonis PA .

In this study, we present data indicating that mammalian stem cell pluripotency-inducing factors are expressed during lens and limb regeneration in newts. The apparent expression even in intact tissues and the ensued regulation during regeneration raises the possibility that these factors might regulate tissue-specific reprogramming and regeneration. Furthermore, these factors should enable us to understand the similarities and differences between animal regeneration in the newt and stem cell strategies in mammals. Developmental Dynamics 238:1613-1616, 2009. (c) 2009 Wiley-Liss, Inc.

PubMed ID: 19384853
PMC ID: PMC2749736
Article link: Dev Dyn
Grant support: [+]

References [+] :
Del Rio-Tsonis, Eye regeneration at the molecular age. 2003, Pubmed, Xenbase

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