Harel A , Chan RC , Lachish-Zalait A , Zimmerman E , Elbaum M , Forbes DJ .

R01 GM-33279 NIGMS NIH HHS , R01 GM033279-20 NIGMS NIH HHS , R01 GM033279 NIGMS NIH HHS

Allen, Deciphering networks of protein interactions at the nuclear pore complex. 2002, Pubmed

Allen, Deciphering networks of protein interactions at the nuclear pore complex. 2002, Pubmed
Askjaer, Ran GTPase cycle and importins alpha and beta are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos. 2002, Pubmed
Bauer, In vitro assembly of coiled bodies in Xenopus egg extract. 1994, Pubmed , Xenbase
Bayliss, Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. 2000, Pubmed
Bayliss, The molecular mechanism of transport of macromolecules through nuclear pore complexes. 2000, Pubmed
Belgareh, An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells. 2001, Pubmed
Ben-Efraim, Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import. 2001, Pubmed
Blow, Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs. 1986, Pubmed , Xenbase
Bodoor, Sequential recruitment of NPC proteins to the nuclear periphery at the end of mitosis. 1999, Pubmed
Boehmer, Depletion of a single nucleoporin, Nup107, prevents the assembly of a subset of nucleoporins into the nuclear pore complex. 2003, Pubmed
Boman, GTP hydrolysis is required for vesicle fusion during nuclear envelope assembly in vitro. 1992, Pubmed , Xenbase
Burke, Remodelling the walls of the nucleus. 2002, Pubmed
Clouse, A Ran-independent pathway for export of spliced mRNA. 2001, Pubmed , Xenbase
Conti, Nucleocytoplasmic transport enters the atomic age. 2001, Pubmed
Cronshaw, Proteomic analysis of the mammalian nuclear pore complex. 2002, Pubmed
Dabauvalle, Spontaneous assembly of pore complex-containing membranes ("annulate lamellae") in Xenopus egg extract in the absence of chromatin. 1991, Pubmed , Xenbase
Daigle, Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells. 2001, Pubmed , Xenbase
Damelin, Nuclear protein transport. 2002, Pubmed
Damelin, Mapping interactions between nuclear transport factors in living cells reveals pathways through the nuclear pore complex. 2000, Pubmed
Dasso, The Ran GTPase: theme and variations. 2002, Pubmed
Drummond, Temporal differences in the appearance of NEP-B78 and an LBR-like protein during Xenopus nuclear envelope reassembly reflect the ordered recruitment of functionally discrete vesicle types. 1999, Pubmed , Xenbase
Drummond, Interference with the cytoplasmic tail of gp210 disrupts "close apposition" of nuclear membranes and blocks nuclear pore dilation. 2002, Pubmed , Xenbase
Ellenberg, Nuclear membrane dynamics and reassembly in living cells: targeting of an inner nuclear membrane protein in interphase and mitosis. 1997, Pubmed
Finlay, Reconstitution of biochemically altered nuclear pores: transport can be eliminated and restored. 1990, Pubmed , Xenbase
Foisner, Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation. 1993, Pubmed
Forbes, Spontaneous formation of nucleus-like structures around bacteriophage DNA microinjected into Xenopus eggs. 1983, Pubmed , Xenbase
Gant, Roles of LAP2 proteins in nuclear assembly and DNA replication: truncated LAP2beta proteins alter lamina assembly, envelope formation, nuclear size, and DNA replication efficiency in Xenopus laevis extracts. 1999, Pubmed , Xenbase
Geles, A role for Caenorhabditis elegans importin IMA-2 in germ line and embryonic mitosis. 2002, Pubmed
Goldberg, Dimples, pores, star-rings, and thin rings on growing nuclear envelopes: evidence for structural intermediates in nuclear pore complex assembly. 1997, Pubmed , Xenbase
Goldman, Nuclear lamins: building blocks of nuclear architecture. 2002, Pubmed
Gruss, Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. 2001, Pubmed , Xenbase
Görlich, Transport between the cell nucleus and the cytoplasm. 1999, Pubmed
Haraguchi, Live fluorescence imaging reveals early recruitment of emerin, LBR, RanBP2, and Nup153 to reforming functional nuclear envelopes. 2000, Pubmed
Harel, Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores. 2003, Pubmed , Xenbase
Heald, Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. 1996, Pubmed , Xenbase
Hetzer, GTP hydrolysis by Ran is required for nuclear envelope assembly. 2000, Pubmed , Xenbase
Hetzer, Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. 2001, Pubmed , Xenbase
Huber, The importin-beta binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro. 2002, Pubmed
Kalab, The ran GTPase regulates mitotic spindle assembly. 1999, Pubmed , Xenbase
Kalab, Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts. 2002, Pubmed , Xenbase
Kutay, Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex. 1997, Pubmed , Xenbase
Lohka, Roles of cytosol and cytoplasmic particles in nuclear envelope assembly and sperm pronuclear formation in cell-free preparations from amphibian eggs. 1984, Pubmed , Xenbase
Lusk, Karyopherins in nuclear pore biogenesis: a role for Kap121p in the assembly of Nup53p into nuclear pore complexes. 2002, Pubmed
Macara, Transport into and out of the nucleus. 2001, Pubmed
Macaulay, Assembly of the nuclear pore: biochemically distinct steps revealed with NEM, GTP gamma S, and BAPTA. 1996, Pubmed , Xenbase
Marelli, A link between the synthesis of nucleoporins and the biogenesis of the nuclear envelope. 2001, Pubmed
Meier, Nuclear pore complex assembly studied with a biochemical assay for annulate lamellae formation. 1995, Pubmed , Xenbase
Melchior, Two-way trafficking with Ran. 1998, Pubmed
Miller, Purification of the vertebrate nuclear pore complex by biochemical criteria. 2000, Pubmed , Xenbase
Nachury, Importin beta is a mitotic target of the small GTPase Ran in spindle assembly. 2001, Pubmed , Xenbase
Newport, Nuclear reconstitution in vitro: stages of assembly around protein-free DNA. 1987, Pubmed , Xenbase
Powers, Reconstituted nuclei depleted of a vertebrate GLFG nuclear pore protein, p97, import but are defective in nuclear growth and replication. 1995, Pubmed , Xenbase
Pu, The balance of RanBP1 and RCC1 is critical for nuclear assembly and nuclear transport. 1997, Pubmed , Xenbase
Raharjo, Nuclear envelope defects associated with LMNA mutations cause dilated cardiomyopathy and Emery-Dreifuss muscular dystrophy. 2001, Pubmed
Rout, The yeast nuclear pore complex: composition, architecture, and transport mechanism. 2000, Pubmed
Rudt, Cytosolic import factor- and Ran-independent nuclear transport of ribosomal protein L5. 2001, Pubmed , Xenbase
Ryan, The Ran GTPase cycle is required for yeast nuclear pore complex assembly. 2003, Pubmed
Schwoebel, The mechanism of inhibition of Ran-dependent nuclear transport by cellular ATP depletion. 2002, Pubmed
Shah, Major binding sites for the nuclear import receptor are the internal nucleoporin Nup153 and the adjacent nuclear filament protein Tpr. 1998, Pubmed , Xenbase
Steggerda, Regulation of nuclear import and export by the GTPase Ran. 2002, Pubmed
Stoffler, The nuclear pore complex: from molecular architecture to functional dynamics. 1999, Pubmed
Takizawa, Ran-independent nuclear import of cyclin B1-Cdc2 by importin beta. 1999, Pubmed
Timinszky, The importin-beta P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope. 2002, Pubmed
Ullman, RNA polymerase III transcription in synthetic nuclei assembled in vitro from defined DNA templates. 1995, Pubmed , Xenbase
Vasu, Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export. 2001, Pubmed , Xenbase
Vasu, Nuclear pores and nuclear assembly. 2001, Pubmed
Walther, The nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteins. 2001, Pubmed , Xenbase
Walther, The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import. 2002, Pubmed , Xenbase
Walther, The conserved Nup107-160 complex is critical for nuclear pore complex assembly. 2003, Pubmed , Xenbase
Weis, Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle. 2003, Pubmed
Wente, A new family of yeast nuclear pore complex proteins. 1992, Pubmed
Wiese, Role of importin-beta in coupling Ran to downstream targets in microtubule assembly. 2001, Pubmed , Xenbase
Yang, Integral membrane proteins of the nuclear envelope are dispersed throughout the endoplasmic reticulum during mitosis. 1997, Pubmed
Zhang, Role of importin-beta in the control of nuclear envelope assembly by Ran. 2002, Pubmed , Xenbase
Zhang, Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly. 2002, Pubmed , Xenbase
Zhang, Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts. 2000, Pubmed , Xenbase
Zhang, Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system. 2001, Pubmed , Xenbase