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Elife
2013 Feb 19;2:e00571. doi: 10.7554/eLife.00571.
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Developing cell biology.
Needleman D
.
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Experiments in Xenopus embryo extracts reveal that changes in cellular biochemistry cause mitotic spindles to decrease in size over the course of early development.
Figure 1. Embryos undergo multiple rounds of rapid division during the early stages of development of many animals. As the cells become progressively smaller, the spindles inside them also decrease in size. Reproduced from Wilson (1897).
Courtois,
The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development.
2012, Pubmed
Courtois,
The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development.
2012,
Pubmed
Goehring,
Organelle growth control through limiting pools of cytoplasmic components.
2012,
Pubmed
Greenan,
Centrosome size sets mitotic spindle length in Caenorhabditis elegans embryos.
2010,
Pubmed
,
Xenbase
Hara,
Cell-size-dependent spindle elongation in the Caenorhabditis elegans early embryo.
2009,
Pubmed
Loughlin,
A computational model predicts Xenopus meiotic spindle organization.
2010,
Pubmed
,
Xenbase
Ohi,
Nonredundant functions of Kinesin-13s during meiotic spindle assembly.
2007,
Pubmed
,
Xenbase
Wilbur,
Mitotic spindle scaling during Xenopus development by kif2a and importin α.
2013,
Pubmed
,
Xenbase
Wühr,
Evidence for an upper limit to mitotic spindle length.
2008,
Pubmed
,
Xenbase
