XB-ART-47844Dev Cell October 14, 2013; 27 (1): 1-2.
Sculpting the nucleus with dynamic microtubules.
How nuclear morphology is regulated during development and disease remains poorly understood. In this issue of Developmental Cell, using a pronuclear assembly assay, Xue et al. (2013) demonstrate that Dppa2, a chromatin-bound microtubule regulator, controls both the morphology and function of the pronucleus by fine-tuning microtubule dynamics.
PubMed ID: 24135226
PMC ID: PMC5439145
Article link: Dev Cell
Genes referenced: dppa2
References [+] :
Carmena, The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. 2012, Pubmed