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Dev Cell October 14, 2013; 27 (1): 1-2.

Sculpting the nucleus with dynamic microtubules.

Guo Y , Zheng Y .

How nuclear morphology is regulated during development and disease remains poorly understood. In this issue of Developmental Cell, using a pronuclear assembly assay, Xue et al. (2013) demonstrate that Dppa2, a chromatin-bound microtubule regulator, controls both the morphology and function of the pronucleus by fine-tuning microtubule dynamics.

PubMed ID: 24135226
PMC ID: PMC5439145
Article link: Dev Cell
Grant support: [+]
Genes referenced: dppa2

References [+] :
Carmena, The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. 2012, Pubmed

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