Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Dev Cell. April 1, 2017; 5 (2): 187-8.

The quest for the holy "G" of chromosomal passengers.

Burke DJ , Stukenberg PT .

Twelve years after reporting a novel chromosomal passenger protein, Mollinari et al. in this issue of Developmental Cell finally report its molecular identification, and the results are stunning. TD-60 is a member of the RCC1 family of guanine nucleotide exchange factors implicating small GTPases in chromosome congression and cytokinesis.

PubMed ID: 12919667
Article link: Dev Cell.

Genes referenced: aurka aurkb incenp kpna1 kpnb1 rac1 ran rcc1 tbx2 tpx2

External Resources:

Mollinari, 2003, Pubmed

Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.9.1
Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556