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XB-ART-4957
Brain Res Mol Brain Res July 23, 2003; 115 (2): 196-201.

Expression of 5-HT2B and 5-HT2C receptor genes is associated with proliferative regions of Xenopus developing brain and eye.

De Lucchini S , Ori M , Nardini M , Marracci S , Nardi I .


Abstract
Here we clone the Xenopus 5-HT2B receptor cDNA and describe its spatio-temporal mRNA expression within the developing larval brain and visual system. Expression of the 5-HT2B transcripts is compared to that of 5-HT2C as well as proliferation and neurogenic markers. In developing brain and retina, 5-HT2B and 2C mRNAs are mainly expressed in proliferative regions. We suggest that these receptors may play a role in the larval secondary neurogenesis by mediating mitogenic effects of serotonin.

PubMed ID: 12877990
Article link: Brain Res Mol Brain Res

Genes referenced: ccnd1 htr2b htr2c notch1


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