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XB-ART-50511
Transcription May 1, 2013; 4 (3): 114-9.

The H2A/H2B-like histone-fold domain proteins at the crossroad between chromatin and different DNA metabolisms.

Gnesutta N , Nardini M , Mantovani R .


Abstract
Core histones are the building block of chromatin and among the most highly conserved proteins in eukaryotes. The related "deviant" histones share the histone-fold domain, and serve various roles in DNA metabolism. We provide here a structural and functional outlook of H2A/H2B-like deviant histones in transcription, replication and remodeling.

PubMed ID: 23756340
PMC ID: PMC4042584
Article link: Transcription


Species referenced: Xenopus
Genes referenced: h2ac21 h2bc21 pole3 pole4 taf11 taf12 taf13 taf4 taf6 taf9b

References [+] :
Aksenova, Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε. 2010, Pubmed