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XB-ART-5340
Cell 2003 May 02;1133:275-6. doi: 10.1016/s0092-8674(03)00317-9.
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p53 and TGF-beta in development: prelude to tumor suppression?

Whitman M , McKeon F .


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Recent work in Xenopus embryos reveals an unexpected developmental role for the tumor suppressor gene p53. This finding may have implications for the evolution of p53, its interaction with Smads in TGF-beta dependent mesoderm specification, and the cooperation among p53 family members.

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Species referenced: Xenopus
Genes referenced: tgfb1 tp53

References :
Cordenonsi, Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads. 2003, Pubmed, Xenbase