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XB-ART-54475
PLoS One January 1, 2018; 13 (1): e0191470.

Cloning and spatiotemporal expression of Xenopus laevis Apolipoprotein CI.

Sridharan J , Haremaki T , Weinstein DC .


Abstract
Apolipoprotein CI (ApoCI) belongs to the Apolipoprotein superfamily, members of which are involved in lipid transport, uptake and homeostasis. Excessive ApoCI has been implicated in atherosclerosis and Alzheimer''s disease in humans. In this study we report the isolation of Xenopus laevis apoCI and describe the expression pattern of this gene during early development, using reverse transcription polymerase chain reaction and whole mount in situ hybridization. Xenopus apoCI is enriched in the dorsal ectoderm during gastrulation, and is subsequently expressed in sensory placodes, neural tube and cranial neural crest. These data suggest as yet uncharacterized roles for ApoCI during early vertebrate embryogenesis.

PubMed ID: 29346450
PMC ID: PMC5773212
Article link: PLoS One
Grant support: [+]
Genes referenced: apoc1 chrd.1 clock frzb2 otx2 pax6 snai2


Article Images: [+] show captions
References:

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