Ultrahigh-resolution optical coherence tomography by broadband continuum generation from a photonic crystal fiber.
We have developed an ultrahigh-resolution optical coherence tomographic system in which broadband continuum generation from a photonic crystal fiber is used to produce high longitudinal resolution. Longitudinal resolution of 1.3-microm has been achieved in a biological tissue by use of continuum light from 800 to 1400 nm. The system employed a dynamic-focusing tracking method to maintain high lateral resolution over a large imaging depth. Subcellular imaging is demonstrated.
PubMed ID: 12656325
Article link: Opt Lett.
Grant support: EB-00255 NIBIB NIH HHS , EB-00293 NIBIB NIH HHS , RR-01192 NCRR NIH HHS