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XB-ART-6817
Mech Dev August 1, 2002; 116 (1-2): 183-6.

Cloning and expression of Xenopus Prickle, an orthologue of a Drosophila planar cell polarity gene.



Abstract
We have cloned Xenopus orthologues of the Drosophila planar cell polarity (PCP) gene Prickle. Xenopus Prickle (XPk) is expressed in tissues at the dorsal midline during gastrulation and early neurulation. XPk is later expressed in a segmental pattern in the presomitic mesoderm and then in recently formed somites. XPk is also expressed in the tailbud, pronephric duct, retina, and the otic vesicle. The complex expression pattern of XPk suggests that PCP signaling is used in a diverse array of developmental processes in vertebrate embryos.

PubMed ID: 12128221
Article link: Mech Dev

Genes referenced: prickle1


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