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Curr Opin Genet Dev August 1, 2002; 12 (4): 452-8.

Early induction of neural crest cells: lessons learned from frog, fish and chick.

The identification of genes in Xenopus, chick and zebrafish expressed early in prospective neural crest (NC) cells has challenged the previous view that the NC is induced during the closure of the neural tube. We compare here the early inductive molecular mechanisms in different organisms and, despite observed differences, propose a general common model for NC induction.

PubMed ID: 12100892
Article link: Curr Opin Genet Dev